Agonist and Antagonist Drug Effects on Adrenoreceptors in Relation to  Bidirectional Movement in Melanophores of Fresh Water Teleost Fish:  <em>Balantiocheilos melanopterus</em> (Bleeker)

Trapti Pathak; Sonia Johri; J.L. Bhat

doi:10.36648/2572-5459.10.2.150

Abstract

Agonist and Antagonist Drug Effects on Adrenoreceptors in Relation to Bidirectional Movement in Melanophores of Fresh Water Teleost Fish: Balantiocheilos melanopterus (Bleeker)

In present study, the scales of Balantiocheilos melanopterus (Bleeker) from dorso-lateral trunk represented the sympathetic-neuro melenophore preparations which shown stimulation with agonist drugs i.e., norepinephrine, salbutamol terbutaline, ephedrine etc., and antagonist drugs also known as the microtubule-disrupting drugs i.e., yohumbine, propranolol, phenoxybenzamine, metoprolol etc. It was investigated that adrenergic agonist drugs are strongly induced pigment innervation in melanophores in dose-dependent means while adrenergic antagonist, also known to block effectively the α2-adrenoceptors, act as inhibitors to the action of adrenergic agonists. Their effects were examined in isolated scale of selected fish by Melenophore Index (MI) and it was concluded that the chromatic fibers of melanophores are adrenoreceptors for bidirectional movement due to presence of microtubules and these cells do possess α2-adrenoceptors also.

Author(s): Trapti Pathak*, Sonia Johri and J.L. Bhat

Abstract | PDF

Share this